Chinese School - AIDS vaccine clinical trial near end

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AIDS vaccine clinical trial near end

www.chinanews.cn 2005-09-19 14:20:19

Chinanews, Nanning, Sept.17 (By Lin Yanhua) - Today, first-phase clinical
research for China-developed AIDS vaccine entered its final stage. The
last batch of volunteers participating in the test were vaccinated with
combined immune vaccines today in Guangxi Autonomous Region's Center for
Disease Prevention and Control. Such vaccinations are expected to
complete at the end of this year and related clinical observation will be
finished next June.
The center's deputy director Chen Jie remarked that the first-phase
clinical research for China-developed AIDS vaccine is composed of eight
batches of volunteers' vaccination in two stages. The first six batches
of volunteers were vaccinated with single-dose vaccine while starting
from the seventh batch, the volunteers will receive combined immune
vaccines (including DNA vaccines and poxvirus vaccines). Volunteers will
first be vaccinated with DNA vaccines as the base and then receive the
vaccine with pox virus-carrier so that the combined immunity of AIDS
vaccine will be finally accomplished.
On March 12th this year, China commenced its first AIDS vaccine test on
human body. The first batch of eight volunteers received the AIDS
vaccine, followed by regular check-up and health examination conducted by
medical staff. After 180 days of observation, no severe adverse reaction
occurred in those eight volunteers and their biochemical indexes seemed
normal. This indicated that observation of the first batch in the
first-phase clinical research for China-developed AIDS vaccine was
completed and the security of such vaccine was initially proven. At
present, volunteers of other batches are in normal health state.
If the research is finished smoothly and recognized by the State Food and
Drug Administration, researchers will start second-phase clinical
research to evaluate the immunogenicity of the vaccine and expand the
scale of security experiment.

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